S.E.M.I.: Side Effects May Include... cover art

Game

S.E.M.I.: Side Effects May Include...

2026 · PC (Microsoft Windows) · Hack and slash/Beat 'em up · Indie · Arcade

About this game

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Screenshots

S.E.M.I.: Side Effects May Include... screenshotS.E.M.I.: Side Effects May Include... screenshotS.E.M.I.: Side Effects May Include... screenshotS.E.M.I.: Side Effects May Include... screenshotS.E.M.I.: Side Effects May Include... screenshotS.E.M.I.: Side Effects May Include... screenshotS.E.M.I.: Side Effects May Include... screenshot
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Game facts

Release date

Jan 23, 2026

Developer

Two Horn Unicorn

Publisher

Two Horn Unicorn

Platforms

PC (Microsoft Windows)

Genres

Hack and slash/Beat 'em up, Indie, Arcade

Themes

Action, Comedy, Party

Game modes

Single player, Multiplayer, Co-operative

Perspective

Third person

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Game data and artwork via IGDB.

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